The use of naloxone in emergency medicine is primarily connected to the treatment of a syndrome known as overdose. which is cause by non-essential use of heroin and certain opioid agonists. The dose of naloxone required to be efficacious depends on the quantity of opioid assumed. its receptorial affinity and its kinetics: in propoxyphene and pentazocine intoxication. https://pipingrockers.shop/product-category/sage/