Orosomucoid like 3 (ORMDL3) encodes an ER-resident transmembrane protein that regulates the activity of serine palmitoyltransferase (SPT). the first and rate-limiting enzyme for sphingolipid biosynthesis in cells. A decade ago. several genome wide association studies revealed single nucleotide polymorphisms associated with increased ORMDL3 protein expression and susceptibility to alle... https://parisnaturalfoodes.shop/product-category/kukui-nut-body-cream/